Infectious Disease Alert – February 1, 2012
February 1, 2012
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Abstract & Commentary: Respiratory infections drive inappropriate antibiotic use in ambulatory pediatrics
A representative analysis of national oral antibiotic prescribing in ambulatory pediatrics was conducted using the National Ambulatory and the National Hospital Ambulatory Medical Care Surveys during 20062008 among patients younger than 18 years of age. -
Special Feature: Telaprevir, Boceprevir for HCV: High Cost may warrant 'criteria for use' policies
Hepatitis C virus (HCV) associated liver disease has affected an estimated 180 million people worldwide, and it continues to be the most common indication for liver transplantation. -
Severe Sepsis and Septic Shock in 2012: What Have We Learned?
When I was a medicine resident 40 years ago just as the first ICUs were being introduced, treatment for life-threatening bacterial infections consisted of antibiotics, control or removal of the primary source, intravenous fluids, and vasopressors. -
The Globalization of Antibiotic Resistance — India and Cambodia
During November, 2011, I attended separate meetings dedicated to exploring the incidence of antimicrobial resistance in two areas of the developing world, India and Cambodia. The first, sponsored jointly by the American Society for Microbiology (ASM), the European Society for Clinical Microbiology and Infectious Diseases (ESCMID), and the Indian Association of Medical Microbiologists (IAMM), was named the "International Workshop on Antimicrobial Resistance" and was held at the Haffkine Institute in Mumbai, India. Organized by Prof. Lance Peterson (ASM representative), Prof. Abhay Chowdhary (Director of Haffkine Institute), Prof. V. Ravi (President of the IAMM), and Prof. Guiseppe Cornaglia (President of ESCMID), the workshop brought together around 250 participants, principally from India, to discuss various aspects of antimicrobial resistance over a 2.5 day program. -
Abstract & Commentary: Absence of pathogens in intestinal tissue of patients with necrotizing enterocolitis
Fresh ileum tissue specimens from infants with NEC or non-NEC diagnoses were provided by the Pathology departments at the children's hospitals at Vanderbilt and at University of Illinois. Standard methods of nucleic acid extraction were employed. -
Updates By Carol A. Kemper, MD, FACP
Following reports of the discovery of a strain of totally-drug resistant M. tuberculosis (TDR-TB) infecting 4 individuals in a Mumbai Hospital this month, another hospital in Bangalore may have identified two additional patients infected with an equally resistant strain of MTb. -
Pharmacology Watch: New, Shorter Treatment Regimen for Tuberculosis
Three months of two drugs administered once weekly is as effective as 9 months of daily isoniazid (INH) for the treatment of latent tuberculosis infection (LTBI), according to a new study. -
Clinical Briefs in Primary Care supplement