In a large pooled database from seven AD clinical trials, the clinical features of early and late-onset AD were compared and contrasted.
Lyme disease with CNS involvement may respond well to oral doxycycline therapy and intravenous antibiotics may not be necessary.
In a detailed clinical analysis of patients with fibromyalgia compared to normal controls, patients with fibromyalgia had significantly lower epidermal nerve fiber density in the distal leg skin biopsies, and distal hypesthesia, compared to normal controls.
Dr. Gauthier reports she receives research support from EMD Serono, Biogen Idec, and Novartis Pharmaceuticals, and is on the speakers bureau for Biogen Idec and Teva Neurosciences.