In a large histopathological study, the distribution of nonheme iron and the expression of iron-related proteins in multiple sclerosis (MS) brains were compared to controls.
Current trials with amyloid antibodies have not shown clinical benefit, but the results suggest that treating patients earlier in the course, or during the presymptomatic period, might be beneficial.
Subjects with Lesch-Nyhan disease and Lesch-Nyhan variant have significant reductions in brain size in the basal ganglia as well as several cortical areas.
An outbreak of fungal meningitis and paraspinal infections occurred over the past year due to contaminated methylprednisolone injections.
Hyperkalemic periodic paralysis has now been well characterized clinically, physiologically, and genetically.